Capsid Geometrical Anatomy (Luque lab)
November 11, 2021
Zoom session
- Zoom recording of Parts 2 and 3.
- Agenda:
- Part 1: Toni Luque provides an update and vision about the tools that the Luque lab has been developing to predict the structural phenotype of viruses from genomic information.
- Part 2: Diana Lee leads a demonstration on how to predict the capsid architecture of tailed phages from their genome.
- Part 3: Diana Lee leads a demonstration on how to predict the capsid architecture of tailed phages from their major capsid protein gene.
Access to the main files for the session
- Lee et al. pre-print 2021-10-01: This pre-print introduces the genome-to-T number and MCP-to-T number models and investigates metagenomically assembled gut phage genomes.
- VAN: Virus Anatomy Navigator: This GitHub repository is the umbrella of the different genotype-to-phenotype viral structural tools that the Luque lab has or will develop. Checkout the workshop branch.
Part 1
Overview. Images extracted from Lee et al. pre-print 2021-10-01.
Tailed phage icosahedral capsids
Genotype-to-phenotype approach
Fishing structures in metagenomes
Part 2
Diana Lee: Genome-to-T-number (G2T) model demonstration
Part 3
Diana Lee: MCP-to-T-number (MCP2T) model demonstration
Closure
- Decide days for UConn visit.
- Heads-up: Assembly Virus Workshop at SDSU (Dec 6 and 8 from 3 pm to 5 pm Pacific Time).